Solid Phase Synthesis

Building complexity with precision

Solid Phase Synthesis

Where efficiency meets innovation

Solid phase synthesis has revolutionized the way complex molecules are assembled, particularly in the fields of peptide and oligonucleotide chemistry. This method involves anchoring a starting material to a solid support, allowing for sequential addition of reagents with intermediate washing steps. The technique offers unparalleled efficiency, purity, and ease of automation, making it indispensable for modern medicinal chemistry.

Our expertise

High efficiency - the ability to wash away excess reagents and by-products after each step results in higher yields and purities.

Automation - the solid phase approach is highly amenable to automation, allowing for rapid synthesis of large compound libraries.

Versatility - solid phase synthesis can be used to create a wide range of molecules, from peptides and oligonucleotides to small organic compounds.

Solid phase synthesis. Building complexity with precision. Where efficiency meets innovation. Discover more!

Applications of solid phase synthesis in drug discovery and development

Peptide synthesis - rapid and efficient assembly of peptides, crucial for drug discovery and therapeutic development.

Oligonucleotide synthesis - advanced techniques to increase the efficiency of oligonucleotide synthesis, enhancing the production of high-quality oligonucleotides for various applications.

Small molecule synthesis - performing a dozen or more types of transformations on solid phase, covering a large portion of the chemical space typically accessed by chemists in wet-lab conditions

Parallel synthesis and combinatorial chemistry - efficient application of combinatorial chemistry approaches in focused library design to cover structure-activity relationships in a rational manner, rapidly generating compound libraries for screening and lead optimization.

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What our clients
say about us

As a reliable partner with a world-class team of chemistry experts, SpiroChem delivers high-quality solutions offering you the ‘best chance of being successful’

Testimonials

“SpiroChem is a reliable partner for our lead optimization programs. We have been working with SpiroChem for several years in a fruitful and trustworthy relationship. The SpiroChem team - based on strong knowledge of synthetic and medicinal chemistry – always performs effectively to boost our structure-activity relationship studies. And when it comes to the synthesis of challenging targets, SpiroChem also solved many synthetic issues with unique and sophisticated ideas that no other CRO can provide. It stimulates us and brings great results and value to our projects. For this reason, SpiroChem is a highly recommended partner for discovery.”