Collaborating with top-notch academic groups to find innovative solutions towards novel structures and expand the toolbox of new chemical transformations is among the many actions that are reinforcing SpiroChem’s strategic growth.
Therefore, we are pleased to announce our collaboration with Dr Kevin Brown and his laboratory (Indiana University), generating an article that was published in the Journal of the American Chemical Society, where we focus on efficient photochemical methodology to deliver disubstituted bicyclo[2.1.1]hexanes.
The full article can be found here: pubs.acs.org
The design and synthesis of novel scaffolds with defined shape, conformational restraint, and functionality is a critical contribution for organic chemistry in the drug discovery process. Thus, SpiroChem continues to enrich the accessible chemical space (we call it the “SpiroChem Enabled Space”) by exploring new shapes and connectivities, with an emphasis on conformationally restricted sp3-rich motifs. We are confident that this will inspire medicinal chemists and unleash their creativity with the availability of such motifs and potential isosteric replacements.
If you want to discuss specific scaffolds for your projects:
This publication is the first of many in the "Escaping Flatland 2022" series. Stay tuned for more.
If you want to be one of the first to know:
