Camp 2: Exploring beyond rule-of-5 modalities

Macrocycles are privileged structures in Medicinal Chemistry as they successfully expand the available chemical space and tackle targets that are not reachable by classical chemistry. The SpiroQUEST™ Library has been carefully designed to include a large number of chemotypes, while covering a drug-like range of parameters.

Let’s work together

The apparent complexity of the structures is decorrelated from their synthetic accessibility.
The chemical space surrounding the SpiroQUEST™ Library is fully enabled thanks to our proprietary platform: SpiroChem guarantees rapid turn-around time for hit validation and downstream optimization work.

We will be happy to support your projects.
For more information, please contact Laurence Jung at laurence.jung@spirochem.com