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New Products & Concept

May 20, 2020

Accelerating fragment-based library generation by coupling high-performance...

Conferences

Feb 26, 2020

SpiroChem at the 10th World ADC in...

Conferences

Feb 03, 2020

SpiroChem at the 2nd Anglo-Swiss Symposium 2020

Expertise of the month

Jan 20, 2020

SpiroKits™

Conferences

Jan 19, 2020

2nd Alpine Winter Conference on Medicinal and...

New Products & Concept

Nov 14, 2019

With SpiroChem, let there be light!

Conferences

Oct 25, 2019

SpiroChem at the symposium of Organic chemistry...

Conferences

Sep 05, 2019

SpiroChem at the 17th Annual Discovery on...

Conferences

Sep 02, 2019

SpiroChem at the 2019 Fall Meeting of...

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Discovery
Process R&D
Technology and Platforms
Compound Collections
News
Careers
About

Get in touch

contact@spirochem.com +41 61 685 9500 Follow us

Informations

Terms & Conditions

Impressum

https://tools.google.com/dlpage/gaoptout
https://allaboutcookies.org/

Stay Connected

Stay inspired with our newsletter subscription, keeping you informed on new concepts, products, solutions & more.

Medicinal Chemistry

Our Mission: Accelerate your project!

Typically : 1-6 chemists

Duration : 3-12+ months

Excellence in chemistry
Creative drug design
Solution and productivity driven
Uncompromised quality

Full MedChem programs or Support for a specific phase:

Hit Validation
Hit/Fragment Expansion
Hit-to-Lead

Lead Optimization
SAR Elucidation
Bioisosteric replacement strategies

Properties Optimization
Back-up programs
IP Evaluation
Patent Filing

Hit Validation
Hit/Fragment Expansion
Hit-to-Lead
Lead Optimization
SAR Elucidation

Bioisosteric replacement strategies
Properties Optimization
Back-up programs
IP Evaluation
Patent Filing

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MedChem Enabling Platforms

Our Mission: Explore new chemical space for you

Typically : 2-5 chemists

Duration : 3-12+ months

Opening of new exit vectors
Late-stage functionalization
Synthesis tractability
Unleashed design

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Fragment Libraries

Our Mission: Address unexplored chemical space and diversity

+700 molecules in stock
Unique design
High sp³ content
Conformationally restricted structures
Scale-up and straightforward analoging guaranteed

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DEL Scaffolds

Our Mission : Offer exclusive scaffolds

Bi- and tri-functionalized scaffolds
Uncharted chemical space
Unique dihedral angles covered
Orthogonal protecting groups
Vectors : COOH, CHO, Aryl halides, Nboc, Nfmoc, boronates

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Route Scouting

Our Mission: Design and implement de novo synthetic routes

Typically: 1-3 chemists

Duration: 3-6+ months

De novo design of synthetic routes to target molecules
Trouble-shooting
Development of efficient in-process controls
Stress test, robustness check
Technology transfer package

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SpiroKits

The must-have medicinal chemistry toolbox designed to:

Provide medchem turnkey solutions
Accelerate projects
Foster chemical space exploration
Support novelty

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Catalog

Our mission: Accelerate your R&D

+13 000 molecules
Innovative building blocks
Purity > 95%
Milligram to hundred gram scale
Short delivery time

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Consulting

Our mission: Share our knowledge

Literature analysis
Analysis of SAR results and proposals
Strategy proposals for ADME optimization
Retrosynthetic analysis
Route scouting proposals
Patent gap analysis
Support for patent filing

*hourly rate, daily rate or project-based fee

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Computational Chemistry

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