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Spirochem
  • Discovery
    • Medicinal chemistry
      • Computer-aided drug design
      • Hit validation
      • Hit to lead
      • Lead optimization
      • Hit/Fragment expansion
      • Properties optimization
      • SAR elucidation
      • Bioisosteric replacement strategies
      • IP evaluation
      • Patent filing
    • Compound collections
      • Macrocycle library
      • Fragment library
      • Virtual library
      • Scaffolds
      • SpiroKits
    • Computational chemistry
    • Early ADME and
      PhysChem properties
  • Process R&D
    • Route scouting
    • Tech transfer
    • Demo batches
      and scale-up
    • Impurity synthesis
      and identification
    • Method development
    • Reference standards
  • Fully integrated services
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  • Technology
    • Computational chemistry
    • AI/ML-ready data
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      • Protein degradation
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      • Other bioconjugates
      • Macrocycles
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      • Oligonucleotide-based therapeutics (OLNs)
    • Specialty techniques
      • Photochemistry
      • Flow chemistry
      • Solid phase synthesis
      • Parallel synthesis
        platforms and high-throughput
        experimentation
      • Linker design
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        electrochemistry
      • Lipids, carbohydrates,
        and applications to drug delivery
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  • Discovery
    Discovery
    • Medicinal chemistry
      Medicinal chemistry
      • Computer-aided drug design
      • Hit validation
      • Hit to lead
      • Lead optimization
      • Hit/fragment expansion
      • Properties optimization
      • SAR elucidation
      • Bioisosteric replacement strategies
      • IP evaluation
      • Patent filing
    • Compound collections
      Compound collections
      • Macrocycle library
      • Fragment library
      • Virtual library
      • Scaffolds
      • SpiroKits
    • Computational chemistry
    • Early ADME and PhysChem properties
  • Process R&D
    Process R&D
    • Route scouting
    • Tech transfer
    • Demo batches and scale-up
    • Impurity synthesis and identification
    • Method development
    • Reference standards
  • Fully integrated services
    Fully integrated services
    • Our expert partner network
    • Consulting
  • Technology
    Technology
    • Computational chemistry
    • AI/ML-ready data, automation and parallelization
    • New modalities
      New modalities
      • Protein degradation
      • Antibody-drug conjugates (ADCs)
      • Other bioconjugates
      • Macrocycles
      • Covalent inhibitors
      • Oligonucleotide-based therapeutics (OLNs)
    • Specialty techniques
      Specialty techniques
      • Photochemistry
      • Flow chemistry
      • Solid phase synthesis
      • Parallel synthesis platforms and high-throughput experimentation
      • Linker design
      • Analytical and preparative electrochemistry
      • Lipids, carbohydrates, and applications to drug delivery
  • Resources
    Resources
    • Press releases
    • News
      News
      • Events, conferences and webinars
      • Newsletter
    • Publications
    • SpiroWebinars
  • Careers
  • About
    About
    • How we work
    • The SpiroBrain
    • Our advantage
    • Our commitment
    • Leadership team
    • Our history
All News

The Success Of Your Project Depends On The Decisions You Make

Oct 13, 2020 Newsletter
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One team
many solutions

Careers

In our culturally diverse environment, characterized by a high ratio of PhD chemists, success is measured based on the efficiency and quality of deliveries and the overall performance of the team.

open positions
SpiroChem
  • Discovery
  • Process R&D
  • Fully Integrated Services
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© SpiroChem 2025

  • Discovery
  • Process R&D
  • Fully Integrated Services
  • Technology
  • Resources
  • Careers
  • About

Get in touch

contact@spirochem.com +41 61 685 9500 Follow us

Informations

  • Terms & Conditions
  • Impressum
    • Privacy Policy
    • https://tools.google.com/dlpage/gaoptout
    • https://allaboutcookies.org/

Stay Connected

Stay inspired with our newsletter subscription, keeping you informed on new concepts, products, solutions & more.

Subscribe

© SpiroChem 2024 | web by kara5.

Medicinal Chemistry

Medicinal Chemistry Medicinal Chemistry

Our Mission: Accelerate your project!

Typically : 1-6 chemists

Duration : 3-12+ months

  • Excellence in chemistry
  • Creative drug design
  • Solution and productivity driven
  • Uncompromised quality

Full MedChem programs or Support for a specific phase:

  • Hit Validation
  • Hit/Fragment Expansion
  • Hit-to-Lead
  • Lead Optimization
  • SAR Elucidation
  • Bioisosteric replacement strategies
  • Properties Optimization
  • Back-up programs
  • IP Evaluation
  • Patent Filing
  • Hit Validation
  • Hit/Fragment Expansion
  • Hit-to-Lead
  • Lead Optimization
  • SAR Elucidation
  • Bioisosteric replacement strategies
  • Properties Optimization
  • Back-up programs
  • IP Evaluation
  • Patent Filing
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Medicinal Chemistry Medicinal Chemistry

MedChem Enabling Platforms

MedChem Enabling Platforms MedChem Enabling Platforms

Our Mission: Explore new chemical space for you

Typically : 2-5 chemists

Duration : 3-12+ months

  • Opening of new exit vectors
  • Late-stage functionalization
  • Synthesis tractability
  • Unleashed design
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MedChem Enabling Platforms MedChem Enabling Platforms

Fragment Libraries

Fragment Libraries Fragment Libraries

Our Mission: Address unexplored chemical space and diversity

  • +700 molecules in stock
  • Unique design
  • High sp3 content
  • Conformationally restricted structures
  • Scale-up and straightforward analoging guaranteed
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Fragment Libraries Fragment Libraries

DEL Scaffolds

DEL Scaffolds DEL Scaffolds

Our Mission : Offer exclusive scaffolds

  • Bi- and tri-functionalized scaffolds
  • Uncharted chemical space
  • Unique dihedral angles covered
  • Orthogonal protecting groups
  • Vectors : COOH, CHO, Aryl halides, Nboc, Nfmoc, boronates
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DEL Scaffolds DEL Scaffolds

Route Scouting

Route Scouting Route Scouting

Our Mission: Design and implement de novo synthetic routes

Typically: 1-3 chemists

Duration: 3-6+ months

  • De novo design of synthetic routes to target molecules
  • Trouble-shooting
  • Development of efficient in-process controls
  • Stress test, robustness check
  • Technology transfer package


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Route Scouting Route Scouting

SpiroKits

SpiroKits SpiroKits

The must-have medicinal chemistry toolbox designed to:

  • Provide medchem turnkey solutions
  • Accelerate projects
  • Foster chemical space exploration
  • Support novelty
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SpiroKits SpiroKits

Catalog

Catalog Catalog

Our mission: Accelerate your R&D

  • +13 000 molecules
  • Innovative building blocks 
  • Purity > 95%
  • Milligram to hundred gram scale
  • Short delivery time
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Catalog Catalog

Consulting

Consulting Consulting

Our mission: Share our knowledge

  • Literature analysis
  • Analysis of SAR results and proposals
  • Strategy proposals for ADME optimization
  • Retrosynthetic analysis
  • Route scouting proposals
  • Patent gap analysis
  • Support for patent filing

*hourly rate, daily rate or project-based fee 

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Consulting Consulting

Computational Chemistry

Computational Chemistry Computational Chemistry

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Computational Chemistry Computational Chemistry

SpiroSpace

SpiroSpace SpiroSpace

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SpiroSpace SpiroSpace
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