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Expertise of the month: Libraries of sp<sup>3</sup>-rich Covalent Fragments and Fragments
Apr 28 2023

Expertise of the month

Expertise of the month: Libraries of sp3-rich Covalent Fragments and Fragments

3D fragments are increasingly being considered as complementary to their 2D counterparts and as crucial components to improve pharmacophore coverage and solubility, leading to better starting points for lead generation.

At SpiroChem, we’re using our knowledge and know-how to design novel sp3-rich fragments with high 3D diversity shape.

Acrylamide derivatives
Propiolamide derivatives
α-Halomethyl amide derivatives
Fluorosulfate derivatives
  • In stock
  • QC certified by HPLC & NMR
  • Available as powder from 1 mg
480 sp3-rich FRAGMENTS
sp3 fragments
sp3-sp3 fragments
sp2-sp3 fragments
  • In stock
  • QC certified by HPLC & NMR
  • Available plated in DMSO
  • Soluble at 100mM in DMSO
  • Standard format : 100µL at 50mM in DMSO
  • More fragments available as powder

We will be happy to support your projects.
For more information, please contact Laurence Jung at laurence.jung@spirochem.com.


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