SpiroChem | Where Chemistry Excellence Accelerates Discovery

Spirochem
Driving innovation in drug discovery and process R&D, offering expert chemistry solutions and seamless support throughout.

Where chemistry excellence accelerates discovery.

Turning hits
into candidates

SpiroChem is a pioneering research partner driving innovation across the drug discovery and process R&D chemistry value chain. With our world-class dedicated experts working seamlessly as an extension of your team, we offer the ‘best chance of being successful’ significantly derisking your research programs. Thanks to our fully integrated discovery services enabled by our high-quality trusted research partner network, we support your hit-to-candidate journey every step of the way.

Get in touch
services

We deliver the most robust science and peace of mind

With a diverse portfolio of solutions.

Driving innovation in drug discovery and process R&D, offering expert chemistry solutions and seamless support throughout.
Discovery

Starting from proprietary libraries to comprehensive high-quality medicinal chemistry services, we offer you the ‘best chance of being successful’ in generating a drug candidate.

Driving innovation in drug discovery and process R&D, offering expert chemistry solutions and seamless support throughout.
Process R&D

We pride ourselves in exceptionally high success rates and are committed to delivering the best quality along your chemical process research & development journey.

Driving innovation in drug discovery and process R&D, offering expert chemistry solutions and seamless support throughout.
Fully Integrated Services

With SpiroChem at the center, our integrated discovery services bring together our trusted research partner network supporting you throughout the discovery process with our hit-to-candidate expertise and project management excellence.

Driving innovation in drug discovery and process R&D, offering expert chemistry solutions and seamless support throughout.
Technology

We combine state-of-the-art techniques with deep expertise to deliver solutions that meet the highest standards of quality and efficiency.

SpiroChem at a glance

Our Services
Products
Screening Libraries
Catalog
Services
Chemical biology
  • Bioconjugates
  • Probes and tools for
    biological investigations
  • Natural product chemistry
Medicinal chemistry
Early PR&D
Screening
  • In silico screening
  • ASMS
  • Crystallography
  • Structural Biology
  • Biophysics
  • Biochemical
  • Cell-based
Focused Libraries
  • Rapid validation
  • Project specific for new modalities
    • Macrocycles
    • PROTACs
    • Fragment expansion
    • Linkers/Payloads
KiloLab

1st kg non-GMP for GLP tox*

Synthetic Chemistry Platforms

Tap into our SpiroBrain - offering collective knowledge of the world’s best chemistry minds.

Our strength lies in our people and the collective knowledge they bring to each solution.

SpiroChem’s success is built upon our highly efficient and dynamic team of experts covering various aspects of chemistry and led by seasoned scientific leaders. We pride ourselves in attracting the most talented chemists to join our collaborative and engaging world-class chemistry team.

How we work

Read what our valued clients and collaborators have to say

Testimonials
Driving innovation in drug discovery and process R&D, offering expert chemistry solutions and seamless support throughout.
Odyssey Therapeutics and SpiroChem collaborated on the synthesis of complex molecules and chemical libraries. The SpiroChem team was highly engaged as we defined the scope and aims of the work. SpiroChem worked quickly to evaluate multiple chemistries in parallel. Together, we defined the most productive and impactful path forward, executing on state-of-the-art, challenging synthetic transformations then quickly converting the results to library production. Our collaboration proceeded smoothly as SpiroChem scientists were model collaborators who communicated promptly, provided very efficient logistics, and exhibited a true can-do spirit. It was a pleasure to work with the SpiroChem team and we look forward to future work together.

Natalie Dales, Chief of Research Operations and Portfolio Strategy and Paul Gormisky, Senior Directory of Chemistry, Odyssey Therapeutics

“The SpiroChem team is an outstanding partner for NBE-Therapeutics for finding and optimizing complex synthesis routes for our linker-payloads. SpiroChem’s Team member’s ingenuity, efficiency and proactive attitude was key in finding novel avenues for synthesizing highly complex and also highly cytotoxic small molecules. Due to the close interactions between our teams, it feels like SpiroChem’s team is part of NBE.”

Ulf Grawunder COO & CDO of NBE-Therapeutics

Driving innovation in drug discovery and process R&D, offering expert chemistry solutions and seamless support throughout.
"SpiroChem's expertise in synthetic chemistry, combined with their sense of urgency, make them an ideal partner for exploring new chemical space. Our critical collaboration on bicycloalkyl bioisosteres was published on ChemMedChem 2017 12 590. I have to highlight the ease of communication and the proactive role of SpiroChem, which we regularly experienced in our interactions. They are brilliant to work with, bother for standard synthesis or more demanding customized building blocks and I would recommend their services to any company seeking pragmatic, cutting-edge solutions."

Dr. Yves P. Auberson, executive director, Global Discovery Chemistry, Novartis Institutes for BioMedical Research and president of EEMC.

"It is with great joy that I am recommending SpiroChem based on the excellent job they did for us; Their high flexibility and reactivity to our fast-changing requests were outstanding. Furthermore, SpiroChem's excellent synthetic expertise enabled access to a key API, which we tested and proved to be the basis for the IP of a complete class of substances. Last but not least, I want to emphasize the outstanding and the fast delivery of the very detailed and precise final report with all the analytical documentation included.”

Dr. Peter C. Sennhenn, CEO of transMedChem Consulting

Driving innovation in drug discovery and process R&D, offering expert chemistry solutions and seamless support throughout.
“We partnered with SpiroChem as part of a pilot structure-based drug design and medicinal chemistry campaign. The outcome was very successful! Despite time, budget and even technical constraints, the SpiroChem team promptly addressed our difficulties providing innovative and unexplored chemical solutions. We were able to design improved compounds, better understand the chemical biology of our project, and lay the foundation for further development campaigns. The SpiroChem Chemistry team has closely supported us through the entire process providing ideas and detailed clarification of the strategies undertaken. A great partnership that I am sure to be continued!”

Professor Gisou van der Goot, VP for Responsible Transformation Head of the Laboratory of Cell and Membrane Biology, EPFL

News and events
Oct 16 2024

SpiroChem, Arctoris and Orion: A Swiss-UK-Finnish Dream Team to Supercharge Drug Discovery

Oct 03 2024

SpiroChem and Arctoris Announce Strategic Partnership and Launch Joint Offering to Accelerate Drug Discovery