The analysis of Fragment-Activity Relationships (FAR) supported by 3D-structure enablement provides design guidelines for Fragment Evolution retaining high ligand efficiency.
It is an efficient tool to :
• generate high-quality leads for “difficult-to-drug” targets, intrinsically disordered protein targets, and targets with transient binding pockets
• identify high-affinity binders for degrader approaches
• explore novel IP space
• SpiroChem has assembled a team of experts in the field of biophysics, crystallography and chemistry to provide its customer with getting access to novel lead-like compound classes in less than 12 months.
